UPO Book

Attività di ricerca

Giulia Pinton is an associate professor in cellular and applied biology (SSD: BIOS10/A). Prof. Pinton is primarily engaged in preclinical research in the field of oncology. Her studies focus on understanding the molecular mechanisms that contribute to cancer development and drug resistance. In particular, her research aims to identify new molecular targets for drug development and to explore novel prospects for the treatment of pleural mesothelioma. Recently, she has concentrated on evaluating the expression and role of the enzyme aldehyde dehydrogenase 1A3 (ALDH1A3) in in vitro 3D models of mesothelioma and glioblastoma, as well as in vivo in a syngeneic murine model of mesothelioma. Additionally, she investigates the roles of two epigenetic players: the histone methyltransferase EZH2 and the demethylase KDM6B, in relation to platinum-resistance in mesotheliomas.

Parole chiave

target-therapy, mesothelioma, epigenetics, drug-resistance 

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