UPO Book

Research Activity

1.   Study of the expression and role of bitter taste receptors (TAS2R) in extra-oral sites such as the respiratory system, musculoskeletal system, and gastrointestinal tract.

2.   Generation of in vitro cellular models starting from urine-derived stem cells (USCs). In particular, a differentiation protocol has been developed to obtain skeletal muscle cells from both wild-type USCs and those engineered via CRISPR/Cas9, in order to model genetic muscle disorders. Work is ongoing to establish neuronal differentiation.

Keywords

bitter taste receptor, muscle biology, stem cells, pharmacology, in vitro model

IRIS